Bible, who did not travel with the team for Saturday's game against Virginia Tech, will remain hospitalized for 30 days, according to O'Brien.
"He'll fight it. If he has a chance to beat it, he'll beat it," O'Brien said.
Last Friday, Bible informed O’Brien that his doctor had advised him against traveling to Virginia Tech. It was the first time Bible missed a game or a practice in 34 years of coaching.
Bible, 56, has been a member of O’Brien’s staff since 1999 at Boston College. In addition to coordinating the offense, he serves as quarterbacks and wide receivers coach for N.C. State.
This is his second stint with the Wolfpack, as he coached quarterbacks and wide receivers under Tom Reed from 1983-85. He has coached two of the last three first-team All-ACC quarterbacks – Matt Ryan at Boston College in 2006 and Russell Wilson at N.C. State in 2008.
"He's a great coach," Wilson said Saturday. "He's helped me tremendously."
In 10 games with Bible calling plays this season, N.C. State has averaged 32.6 points and 413.2 yards per game. Both of those numbers ranked third in the ACC.
-- Ken Tysiac